From Longman Dictionary of Contemporary Englishdosedose1 /dəʊs $ doʊs/ ●●○ noun [countable] 1 MDthe amount of a medicine or a drug that you should takedose of Never exceed the recommended dose of painkillers.high/low dose Start with a low dose and increase it.2 UNPLEASANTan amount of something that you do or experience at one time, especially something unpleasanta bad/mild dose of flu British English (=making you feel very ill or only slightly ill) Dave had a bad dose of flu.lethal/fatal dose (of something) (=an amount that kills) a lethal dose of radiation I quite like Jamie in small doses
(=in limited amounts but not a lot or often).3 → like a dose of saltsCOLLOCATIONSadjectivesa high/large doseHigh doses of the drug can have bad side effects.a low/small doseTreatment should be started with a small dose.a daily doseThe study shows that a daily dose of aspirin may reduce the risk of developing bowel cancer.the recommended dose (=recommended by medical experts)The current recommended dose is 250 mg a day.a lethal/fatal dose (=an amount that kills you)She took a lethal dose of painkillers.a single doseThe medicine is given as a single dose.verbstake a dose of somethingHe had taken his usual dose of sleeping pills.give somebody a doseA nurse came in to give me a dose of antibiotics.exceed the dose (=take more of a medicine than is recommended)You should take care not to exceed the recommended dose of paracetamol.
Examples from the Corpusdose• The Cosbys are getting a dose of what families of homicide and fatal accident victims get routinely.• She was given a dose of Hyper. 30 from her first-aid kit and sent to the neurologist.• Finding such a dose response would have made the case stronger.• A dose of old-fashioned repression dealt with some of the bold exceptions.• The banks need a healthy dose of competition.• The designation was made because at high doses, alcohol slows down the central nervous system.• About that proposition, a large dose of skepticism is in order.• The laxative dose required to treat constipation in the young child is much higher than the suggested doses on the label.high/low dose• Digitalis, a heart drug that can be fatal in higher doses, is derived from the foxglove plant.• Some side effects of high doses include acne, oily skin and insomnia.• Certain individuals get sleepy on low doses of alcohol and revved up on high doses-exactly the reverse of what most people experience.• Either lower or higher doses are then injected serially until the weal or the symptoms disappear.• Dissociation of initiation from propagation probably accounts for abortive spikes such as those observed in HeLa cells responding to low doses of histamine.• Drowsiness, impaired cognitive function, and impotence may be a problem with higher doses.• Astra refuses to conduct further rat studies with lower doses of ranitidine, saying that this is Glaxo's job.• In those with non-sustained ventricular tachycardia during electrocardiographic monitoring treatment with low dose amiodarone has been shown to be effective.in small doses• Many of these schemes have been tried before in small doses.• Problems with diamorphine include vomiting, bradycardia, and hypotension, but in small doses diamorphine is better than any sedative.• Prague was high on our list, and Paris, as a tonic, to be taken frequently in small doses.• This can be infectious in small doses, and her catchy anthem, Finally, is pop at its most celebratory.• Knock! jokes are okay in small doses - like one every second leap year.• It's a very amusing book if read in small doses.