the feeling of being annoyed about something, especially something that happens repeatedly or for a long time:
The heavy traffic is a constant source of irritation.
The doctor's irritation at being interrupted showed.
something that makes you annoyed:
The children are just an irritation for him when he's trying to work.
a painful, sore feeling on a part of your body:
The astringent can cause irritation to sensitive skin.
a throat irritation