1 [intransitive and transitive]
if something prickles your skin, it makes it sting slightly:
A cold breeze prickled his face.
His hair prickled my neck.
He felt sweat prickle on his forehead.
if your skin prickles, it begins to sting slightly:
Her skin was prickling uncomfortably.
3 [intransitive] British English
if your eyes prickle, they sting slightly because you are going to cry:
She felt her eyes prickle. 'It was awful,' she whispered.
My eyes prickled with tears.