a humorous play by Shakespeare about two sets of identical twins (=two children born to the same mother at the same time, who look exactly the same). There are many confusing and amusing situations because the other characters think that they are dealing with one twin when in fact they are dealing with the other. The phrase 'a comedy of errors' is often used to describe a situation that is so full of mistakes and problems that it seems funny.
Definition from the Longman Dictionary of Contemporary English Advanced Learner's Dictionary.
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