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From Longman Dictionary of Contemporary Englishdepopulatede‧pop‧u‧late /ˌdiːˈpɒpjəleɪt $ -ˈpɑːp-/ verb [transitive]  REDUCEto greatly reduce the number of people living in a particular area Disease depopulated the whole region.depopulation /diːˌpɒpjəˈleɪʃən $ -ˌpɑːp-/ noun [uncountable]
Examples from the Corpus
depopulateShe wants to depopulate the earth and liberate the plants.
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