She's doing everything she can to make life difficult for him.
3someone who is difficult never seems pleased or satisfied [= awkward]:
Don't be so difficult!
a difficult customer
WORD FOCUS: difficult WORD FOCUS: difficult difficult to do:hard, tough, challenging, daunting difficult and needing a lot of physical effort:tough, strenuous, back-breaking, gruelling, arduous, punishing difficult to deal with or talk about:tricky, awkward, delicate, sensitive, touchy words for describing a difficult person:awkward, trying words for describing difficult conditions:adverse, hostile
Definition from the Longman Dictionary of Contemporary English Advanced Learner's Dictionary.