Longman Dictionary of Contemporary English homepage

Date: 1800-1900
Origin: knacker 'horse-killer'; KNACKERS' YARD

knacker

verb
     
knack‧er [transitive] British English spoken informal
1 to become extremely tired [= exhaust]
knacker yourself (out)
Slow down - you'll knacker yourself out!
2

knacker your elbow/hand etc

to hurt your elbow etc so that you cannot use it

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