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knockout

2 adjective
     
knockout2 informal
1

knockout punch/blow

a) a hard hit that knocks someone down so that they cannot get up again
b) an action or event that causes defeat or failure:
High interest rates have been a knockout blow to the business.
2 relating to a type of competition in which only the winning players or teams at each stage continue to play:
Scotland's failure to get through the knockout stage of the competition
3

knockout pills/drops etc

pills etc that make someone unconscious

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