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loose

2 verb
     
loose2 [transitive] literary
1 to make something unpleasant begin:
And now the anger Maggie had feared was loosed.
2 to make something loose or to untie someone or something, especially an animal
3 to fire an arrow, a bullet from a gun etc

loose something on/upon somebody/something

phrasal verb
literary to allow something dangerous or harmful to begin to affect a situation or other people:
the evils loosed upon humanity in World War II

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