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1 clever at controlling or deceiving people to get what you want - used in order to show disapproval : 
She was sly, selfish, and manipulative.
She was sly, selfish, and manipulative.2 technical relating to the ability to handle objects in a skilful way : Before a child can learn a musical instrument he or she first needs to acquire the necessary manipulative skills.
Before a child can learn a musical instrument he or she first needs to acquire the necessary manipulative skills.3 [only before noun] technicalMH relating to the skill of moving bones and joints into the correct position
