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re‧vers‧al

1 [uncountable and countable] a change to an opposite arrangement, process, or way of doing something [↪ turnaround]
Some Internet firms have suffered a painful reversal of fortune (=they were successful but now they are not).
Some Internet firms have suffered a painful reversal of fortune (=they were successful but now they are not).2 [countable] a failure or other problem that prevents you from being able to do what you want :
In spite of setbacks and reversals, his business was at last making money.
In spite of setbacks and reversals, his business was at last making money.