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sig‧nif‧i‧cant‧ly S3 W2

1 in an important way or to an important degree :
Health problems can be significantly reduced by careful diet.
Methods used by younger teachers differ significantly from those used by older ones.
Health problems can be significantly reduced by careful diet.
Methods used by younger teachers differ significantly from those used by older ones.2 [sentence adverb] used to say that something is very important :
The Democrats, significantly, finished well behind the Green Party.
The Democrats, significantly, finished well behind the Green Party.3 in a way that seems to have a special meaning :
George paused, and glanced significantly in my direction.
George paused, and glanced significantly in my direction.