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2 verb
1 [transitive] to use something new or different instead of something else
substitute something for something
The recipe says you can substitute yoghurt for the sour cream.
2 [intransitive] to do someone's job until the person who usually does it is able to do it again
substitute for
Bill substituted for Larry, who was off sick.
3 [transitive] to replace someone with another person especially another player:
Michael Owen had to be substituted after 20 minutes on the field.

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