used to say that something did actually happen in the way that you said it would:
Sure enough, Mike managed to get lost.
used to say 'yes' to someone:
'Can you give me a ride to work tomorrow?' 'Sure.'
used as a reply when you accept thanks from someone:
accept thanksAmerican English spoken
'Thanks for your help, Karen.' 'Sure.'
used to emphasize a statement:
emphasizeAmerican English informal
It sure is hot out here.
I sure hope they get there all right.
used at the beginning of a statement admitting that something is true, especially before adding something very different:
Sure Joey's happy now, but will it last?