English version

two/three strikes against somebody/something

From Longman Dictionary of Contemporary Englishtwo/three strikes against somebody/somethingtwo/three strikes against somebody/somethingAmerican English a condition or situation that makes it extremely difficult for someone or something to be successful Children from poor backgrounds have two strikes against them by the time they begin school. strike
Examples from the Corpus
two/three strikes against somebody/somethingFor the younger pilots, I had two strikes against me before I even began that were impossible to overcome.Generally, unless batters have two strikes against them, Bosley doesn't want them to swing at high strikes.
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